GMIP Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GMIP Polyclonal antibody
Uniprot No.：

Q9P107
基因名：

GMIP
别名：

ARHGAP46 antibody; GEM interacting protein antibody; GEM-interacting protein antibody; GMIP antibody; GMIP_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human GEM-interacting protein (719-858AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
基因功能参考文献：
1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages PMID: 25173885
2. during exocytosis, actin depolymerization commences near the secretory organelle, not the plasma membrane, and secretory granules use a JFC1- and GMIP-dependent molecular mechanism to traverse cortical actin. PMID: 22438581
3. signalling pathways controlled by two proteins of the Ras superfamily, RhoA and Gem, are linked via the action of the RhoGAP protein Gmip PMID: 12093360
4. Variations in the GMIP gene can confer susceptibility to major depressive disorder. PMID: 16086184
数据库链接：

HGNC: 24852

OMIM: 609694

KEGG: hsa:51291

STRING: 9606.ENSP00000203556

UniGene: Hs.49427