GMDS Antibody, FITC conjugated
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中文名称:GMDS兔多克隆抗体, FITC偶联
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货号:CSB-PA009569LC01HU
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) GMDS Polyclonal antibody
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Uniprot No.:
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基因名:GMDS
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别名:GDP D mannose dehydratase antibody; GDP mannose 4 6 dehydratase antibody; GDP-D-mannose dehydratase antibody; GDP-mannose 4,6 dehydratase antibody; GMD antibody; Gmds antibody; GMDS_HUMAN antibody; OTTHUMP00000017756 antibody; OTTHUMP00000232770 antibody; SDR3E1 antibody; Short chain dehydrogenase/reductase family 3E member 1 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human GDP-mannose 4,6 dehydratase protein (243-346AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:FITC
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相关产品
靶点详情
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功能:Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
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基因功能参考文献:
- Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
- These data demonstrate involvement of GMDS mutation in the progression of colorectal cancer. PMID: 23922970
- Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC. PMID: 23730929
- GMD inhibits tankyrase 1 poly(ADP-ribose) polymerase activity in vitro, dependent on the GMD tankyrase 1 binding motif. In vivo, depletion of GMD led to degradation of tankyrase 1, dependent on the catalytic PARP activity of tankyrase 1. PMID: 22645305
- Results indicate that GMDS regulates the formation of secondary complex II from the primary DISC independent of direct fucosylation of death receptors. PMID: 22027835
- FX takes part in the cascade of events leading to the extravasation of activated lymphocytes. PMID: 11831876
- Deficiency of GMDS leads to escape from natural killer cell-mediated tumor surveillance through modulation of TRAIL signaling. PMID: 19361506
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蛋白家族:NAD(P)-dependent epimerase/dehydratase family, GDP-mannose 4,6-dehydratase subfamily
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数据库链接:
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