GDPD2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GDPD2 Polyclonal antibody
Uniprot No.：

Q9HCC8
基因名：

GDPD2
别名：

GDPD2; GDE3; OBDPF; UNQ1935/PRO4418; Glycerophosphoinositol inositolphosphodiesterase GDPD2; Glycerophosphodiester phosphodiesterase 3; Glycerophosphodiester phosphodiesterase domain-containing protein 2; Osteoblast differentiation promoting factor
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Glycerophosphoinositol inositolphosphodiesterase GDPD2 protein (210-490AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton.
基因功能参考文献：
1. The results establish GDE3 as a negative regulator of the uPAR signaling network and, furthermore, highlight GPI-anchor hydrolysis as a cell-intrinsic mechanism to alter cell behavior. PMID: 28849762
2. GDE3 is a novel seven-transmembrane protein with a GP-PDE-like extracellular motif expressed during osteoblast differentiation that accelerates the program of osteoblast differentiation and is involved in morphological change of cells PMID: 12933806
3. GDE3 substrate GroPIns is a candidate mediator for osteoblast proliferation PMID: 19596859
亚细胞定位：

Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton.
蛋白家族：

Glycerophosphoryl diester phosphodiesterase family
数据库链接：

HGNC: 25974

OMIM: 300940

KEGG: hsa:54857

UniGene: Hs.438712