GAREM1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GAREM1 Polyclonal antibody
Uniprot No.：

Q9H706
基因名：

GAREM1
别名：

GAREM1 antibody; C18orf11 antibody; FAM59A antibody; GAREM antibody; GRB2-associated and regulator of MAPK protein 1 antibody; GRB2-associated and regulator of MAPK1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human GRB2-associated and regulator of MAPK protein (12-320AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.
基因功能参考文献：
1. We have provided evidence that GAREM1 is involved in the PR interval of ECGs. These findings increase our understanding of the regulatory signals of heart rhythm through intracardiac ganglia of the autonomic nervous system and can be used to guide the development of a therapeutic target for heart conditions, such as atrial fibrillation. PMID: 29273731
2. suggest that the interplay between 14-3-3, SAM domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells. PMID: 26164232
3. Data indicate that a subtype of GAREM, GAREM2, is specifically expressed in the mouse, rat, and human brain. PMID: 24003223
4. Extracellular signal-regulated kinase activation in response to epidermal growth factor stimulation is regulated by the expression of GAREM in COS-7 and HeLa cells. PMID: 19509291
蛋白家族：

GAREM family
组织特异性：

Isoform 1 is ubiquitously expressed.
数据库链接：

HGNC: 26136

KEGG: hsa:64762

UniGene: Hs.444314