GABRQ Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GABRQ Polyclonal antibody
Uniprot No.：

Q9UN88
基因名：

GABRQ
别名：

GABRQ antibody; Gamma-aminobutyric acid receptor subunit theta antibody; GABA(A) receptor subunit theta antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Gamma-aminobutyric acid receptor subunit theta protein (348-611AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
基因功能参考文献：
1. We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA) receptor subunit-encoding genes, GABRQ and GABRA3.this is the first report of ASD patients with truncating mutations in GABA receptors genes. PMID: 23169495
2. GABRQ plays important roles in hepatocellular carcinoma development and progression PMID: 22690081
3. single nucleotide polymorphisms studied in the GABRA4, GABRE, and GABRQ genes are not related to the risk for familial ET. PMID: 21422964
4. Although GABRQ genes did not show positive association, further studies are necessary to consider the role of other GABA receptor genes in migraine susceptibility PMID: 19087248
亚细胞定位：

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
蛋白家族：

Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRQ sub-subfamily
数据库链接：

HGNC: 14454

OMIM: 300349

KEGG: hsa:55879

STRING: 9606.ENSP00000359329

UniGene: Hs.283081