G2E3 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) G2E3 Polyclonal antibody
Uniprot No.：

Q7L622
基因名：

G2E3
别名：

G2E3 antibody; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase antibody; EC 2.3.2.26 antibody; G2/M phase-specific HECT-type E3 ubiquitin transferase antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
基因功能参考文献：
1. Results suggest that G2E3 is a molecular determinant of the DDR and cell survival. PMID: 25593194
2. Cell cycle phase-specific expression and highly regulated subcellular localization of G2E3 suggest a possible role in cell cycle regulation and the cellular response to DNA damage. PMID: 17239372
亚细胞定位：

Nucleus, nucleolus. Cytoplasm.
组织特异性：

Predominantly expressed in brain, liver, kidney, testes and ovary.
数据库链接：

HGNC: 20338

OMIM: 611299

KEGG: hsa:55632

STRING: 9606.ENSP00000206595

UniGene: Hs.509008