FBXW10 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) FBXW10 Polyclonal antibody
Uniprot No.：

Q5XX13
基因名：

FBXW10
别名：

FBXW10 antibody; F-box/WD repeat-containing protein 10 antibody; F-box and WD-40 domain-containing protein 10 antibody; Ubiquitin ligase-specificity factor antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
基因功能参考文献：
1. O-GlcNAcylation is involved in the regulation of ubiquitination-related genes including FBXW10 PMID: 23899520
2. Mislocalized lamins can induce ubiquitin-mediated proteasomal degradation of certain HP1 isoforms by activation of FBXW10, a member of the F-box family of proteins that is involved in E3 ubiquitin ligase activity. PMID: 20498703
数据库链接：

HGNC: 1211

OMIM: 611679

KEGG: hsa:10517

STRING: 9606.ENSP00000379026

UniGene: Hs.592128