FBXL22 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) FBXL22 Polyclonal antibody
Uniprot No.：

Q6P050
基因名：

FBXL22
别名：

FBXL22F-box and leucine-rich protein 22 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human F-box and leucine-rich protein 22 protein (123-229AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).
基因功能参考文献：
1. Fbxl22 promotes the proteasome-dependent degradation of sarcomeric proteins and is essential for maintenance of normal contractile function. PMID: 22972877
亚细胞定位：

Cytoplasm, myofibril, sarcomere, Z line.
组织特异性：

Enriched in cardiac muscle.
数据库链接：

HGNC: 27537

OMIM: 609088

KEGG: hsa:283807

UniGene: Hs.631163