FBXL20 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) FBXL20 Polyclonal antibody
Uniprot No.：

Q96IG2
基因名：

FBXL20
别名：

FBXL20 antibody; FBL2F-box/LRR-repeat protein 20 antibody; F-box and leucine-rich repeat protein 20 antibody; F-box/LRR-repeat protein 2-like antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human F-box/LRR-repeat protein 20 protein (1-137AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.
基因功能参考文献：
1. which provides a signal to promote its ubiquitination and proteasomal degradation mediated by FBXL20 and the associated Skp1-Cullin1 complex, leading to inhibition of autophagy and receptor endocytosis PMID: 25593308
2. study concludes FBXL20 plays an essential role in the carcinogenesis of colorectal adenocarcinoma and promotes carcinogenesis through the regulation of the Wnt signaling pathway and caspase activation PMID: 23023584
亚细胞定位：

Cytoplasm.
数据库链接：

HGNC: 24679

OMIM: 609086

KEGG: hsa:84961

STRING: 9606.ENSP00000264658

UniGene: Hs.462946