ETV2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ETV2 Polyclonal antibody
Uniprot No.：

O00321
基因名：

ETV2
别名：

ETV2 antibody; ER71 antibody; ETSRP71ETS translocation variant 2 antibody; Ets-related protein 71 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human ETS translocation variant 2 protein (74-201AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
基因功能参考文献：
1. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. PMID: 28026128
2. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. PMID: 27488544
3. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. PMID: 28003219
4. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. PMID: 25540418
5. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp PMID: 18270322
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亚细胞定位：

Nucleus.
蛋白家族：

ETS family
数据库链接：

HGNC: 3491

OMIM: 609358

KEGG: hsa:2116

STRING: 9606.ENSP00000384524

UniGene: Hs.194061