EMB Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) EMB Polyclonal antibody
Uniprot No.：

Q6PCB8
基因名：

EMB
别名：

Emb antibody; EMB_HUMAN antibody; Embigin antibody; Embigin homolog (mouse) antibody; embigin homolog antibody; MGC71745 antibody; OTTHUMP00000161812 antibody; OTTHUMP00000221477 antibody; OTTHUMP00000221478 antibody; OTTHUMP00000221479 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Embigin protein (285-327AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
基因功能参考文献：
1. Study reports elevated expression of Embigin in pancreatic ductal adenocarcinoma and shows its novel functions in regulating cell proliferation, migration, and invasion. PMID: 25773908
2. embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors PMID: 26090721
3. Data show that Gp70 (embigin) was negative in all normal, adjacent non-neoplastic and PIN lesions and only a very small percentage of cases. PMID: 21787388
4. Reports the original cloning of the mouse embigin gene, referred to as gp70, from embryonal carcinoma cells. PMID: 2963822
亚细胞定位：

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
数据库链接：

HGNC: 30465

OMIM: 615669

KEGG: hsa:133418

STRING: 9606.ENSP00000302289

UniGene: Hs.561411