DPYSL4 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DPYSL4 Polyclonal antibody
Uniprot No.：

O14531
基因名：

DPYSL4
别名：

Collapsin response mediator protein 3 antibody; CRMP 3 antibody; CRMP-3 antibody; CRMP3 antibody; Dihydropyrimidinase like 4 antibody; Dihydropyrimidinase related protein 4 antibody; Dihydropyrimidinase-related protein 4 antibody; DPYL4_HUMAN antibody; DPYSL4 antibody; DRP 4 antibody; DRP-4 antibody; DRP4 antibody; ULIP 4 antibody; ULIP-4 antibody; ULIP4 antibody; UNC33 like phosphoprotein 4 antibody; UNC33-like phosphoprotein 4 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Dihydropyrimidinase-related protein 4 protein (280-560AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
基因功能参考文献：
1. DPYSL4 plays a key role in the tumor-suppressor function of p53 by regulating oxidative phosphorylation and the cellular energy supply via its association with mitochondrial supercomplexes, possibly linking to the pathophysiology of both cancer and obesity. PMID: 30061407
2. DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage PMID: 20499313
3. Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. PMID: 11771764
亚细胞定位：

Cytoplasm.
蛋白家族：

Metallo-dependent hydrolases superfamily, Hydantoinase/dihydropyrimidinase family
数据库链接：

HGNC: 3016

OMIM: 608407

KEGG: hsa:10570

STRING: 9606.ENSP00000339850

UniGene: Hs.100058