DNASE2B Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody
Uniprot No.：

Q8WZ79
基因名：

DNASE2B
别名：

DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
基因功能参考文献：
1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
亚细胞定位：

Lysosome.
蛋白家族：

DNase II family
组织特异性：

Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
数据库链接：

HGNC: 28875

OMIM: 608057

KEGG: hsa:58511

STRING: 9606.ENSP00000359699

UniGene: Hs.129142