Your Good Partner in Biology Research

中文简体

CSF2｜ CTLA4｜ DLL3｜ EGFR｜ IL4｜ IL4R｜ LAG3｜ MSTN｜ NECTIN4｜ NT5E｜ SEZ6｜ TM4SF1｜ TNFSF13｜ TPO

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. DDX39A Antibody

DDX39A Antibody

说明书
  • 中文名称：
    DDX39A兔多克隆抗体
  • 货号：
    CSB-PA006620ESR2HU
  • 规格：
    ￥440
  • 图片：
    • Western blot
      All lanes: ATP-dependent RNA helicase DDX39A antibody at 2μg/ml
      Lane 1: A431 whole cell lysate
      Lane 2: 293T whole cell lysate
      Lane 3: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50, 37, 31 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA006620ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA006620ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DDX39A Polyclonal antibody
  • Uniprot No.：
    O00148
  • 基因名：
    DDX39A
  • 别名：
    DDX39A antibody; DDX39 antibody; ATP-dependent RNA helicase DDX39A antibody; EC 3.6.4.13 antibody; DEAD box protein 39 antibody; Nuclear RNA helicase URH49 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ATP-dependent RNA helicase DDX39A protein (178-427AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
    Immunohistochemistry (IHC) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

相关产品

DDX39A antibodies

DDX39A Proteins

靶点详情

  • 功能：
    Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus.
  • 基因功能参考文献：
    1. DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation PMID: 28025139
    2. DDX39A is a potential biomarker for unfavorable neuroblastoma PMID: 26469522
    3. The protein levels of DDX39 were found to be higher in malignant pleural mesothelioma cell lines compared to normal pleural mesothelial cells. PMID: 23749908
    4. Results suggest that DDX39 is a suppressor of invasion and loss of its function predicts disease progression in bladder cancers. PMID: 22494014
    5. #NAME? PMID: 22119546
    6. Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection PMID: 21388492
    7. UAP56 and URH49 exhibit an intrinsic CRM1-independent nucleocytoplasmic shuttling PMID: 21799930
    8. Mx proteins exert their antiviral activity against IAV by interfering with the function of the RNA helicases UAP56 and URH49 PMID: 21859714
    9. Data show that the two closely related RNA helicases UAP56 and URH49 have evolved to form distinct mRNA export machineries, which regulate mitosis at different steps. PMID: 20573985
    10. Using a UL69 viral mutant that is unable to bind UAP56 and URH49, the authors demonstrated that UL69's interaction with UAP56 or URH49 does not contribute to the growth phenotype associated with the UL69 deletion mutant. PMID: 20610707
    11. Regulation of URH49 mRNA expression and comparison with the related UAP56 RNA helicase. PMID: 15047853
    12. Reducing the expression of UAP56 and URH49 resulted in a reduction in reporter gene expression as well as cell death within 72 h suggest that both helicases have essential but largely overlapping functions in the processing and export of mammalian mRNAs. PMID: 16949217
    13. CIP29 physically and functionally associates with DDX39, suggesting their cooperation in the RNA metabolism. PMID: 17196963
    14. DDX39 is a novel RNA helicase capable of promoting cancer cell growth PMID: 17548965

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
  • 蛋白家族：
    DEAD box helicase family, DECD subfamily
  • 组织特异性：
    Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland.
  • 数据库链接：

    HGNC: 17821

    KEGG: hsa:10212

    STRING: 9606.ENSP00000242776

    UniGene: Hs.311609

Most popular with customers

产品中心
特别关注


X
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |