DAZAP2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DAZAP2 Polyclonal antibody
Uniprot No.：

Q15038
基因名：

DAZAP2
别名：

DAZAP2 antibody; KIAA0058DAZ-associated protein 2 antibody; Deleted in azoospermia-associated protein 2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human DAZ-associated protein 2 protein (1-168AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能参考文献：
1. methylation of DAZAP2 promoter was involved in downregulation of DAZAP2 in multiple myeloma cells. PMID: 22792345
2. In summary we established a new mechanism of IL17RB regulation-Smurf2 dependent degradation of its adaptor protein DAZAP2. PMID: 22070932
3. Lys residues might play important roles in regulating the intracellular dynamics of the PRTB protein.K153 in human PRTB is essential for its ubiquitin-dependent degradation PMID: 21274613
4. DAZAP2 is downregulated in multiple myeloma samples and it may be a signal molecule in multiple myeloma cells. DAZAP2 is involved in the pathogenesis of MM PMID: 17935665
亚细胞定位：

Cytoplasm. Nucleus. Note=Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.
组织特异性：

Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Down-regulated in multiple myeloma.
数据库链接：

HGNC: 2684

OMIM: 607431

KEGG: hsa:9802

STRING: 9606.ENSP00000448051

UniGene: Hs.369761