DAP Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DAP Polyclonal antibody
Uniprot No.：

P51397
基因名：

DAP
别名：

DAP 1 antibody; Dap antibody; DAP-1 antibody; DAP1_HUMAN antibody; Death associated protein 1 antibody; Death associated protein antibody; Death-associated protein 1 antibody; MGC99796 antibody; OTTHUMP00000161670 antibody; OTTHUMP00000221331 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Death-associated protein 1 protein (2-102AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.
基因功能参考文献：
1. DAP1 may have an important role in cell adhesion, migration and growth in the context of breast cancer and has significant associations with the apoptosis pathway. PMID: 25530065
2. DAP1 was found to be correlated with disease progression and long-term survival of the colorectal patients. DAP1 is also a pivotal regulator of the growth and apoptosis and cellular response to chemotherapy agents. PMID: 24270644
3. This study demonstrates an inverse association between DAP1 mRNA levels and tumour stage and clinical outcome in breast cancer PMID: 22798505
4. Mapping of the phosphorylation sites and analysis of phosphorylation mutants indicated that DAP1 is functionally silenced in growing cells through mTOR-dependent phosphorylations on Ser3 and Ser51 PMID: 20537536
数据库链接：

HGNC: 2672

OMIM: 600954

KEGG: hsa:1611

STRING: 9606.ENSP00000230895

UniGene: Hs.75189