Your Good Partner in Biology Research

中文简体

CSF2｜ CTLA4｜ DLL3｜ EGFR｜ IL4｜ IL4R｜ LAG3｜ MSTN｜ NECTIN4｜ NT5E｜ SEZ6｜ TM4SF1｜ TNFSF13｜ TPO

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. Clec4g Antibody

Clec4g Antibody

说明书
  • 中文名称：
    Clec4g Antibody
  • 货号：
    CSB-PA803912ZA01MO
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: Clec4g Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Clec4g Polyclonal antibody
  • Uniprot No.：
    Q8BNX1
  • 基因名：
    Clec4g
  • 别名：
    C-type lectin domain family 4 member G, Clec4g
  • 宿主：
    Rabbit
  • 反应种属：
    Mus musculus
  • 免疫原：
    Recombinant Mus musculus Clec4g protein (52-294aa)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

相关产品

Clec4g Proteins

靶点详情

  • 功能：
    Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner.
  • 基因功能参考文献：
    1. This study shows that C-type lectin LSECtin, a member of the DC-SIGN family, is a novel liver regulator for natural killer cells (NK cells). LSECtin could bind to NK cells in a carbohydrate-dependent manner and could regulate the number of hepatic NK cells. PMID: 27184407
    2. Data show that C-type lectin-like domain family 4, member g (Clec4g) suppresses beta-Site amyloid precursor protein cleaving enzyme-1 (BACE1)-mediated amyloid-beta (Abeta) peptides generation. PMID: 25957769
    3. When expressed in B16 melanoma cells, LSECtin promoted tumor growth, whereas its blockade slowed tumor growth in either wild-type or LSECtin-deficient mice. PMID: 24769443
    4. LSECtin-mediated signaling up-regulates the threshold of CD4(+) T cell activation via tuning the expression of Cbl-b. PMID: 22884358
    5. LSECtin may facilitate the reduction of liver inflammation at the cost of delaying virus clearance, an effect that might be hijacked by the virus as an escape mechanism. PMID: 23487419
    6. The studies provide a basis for using mouse LSECtin, and knockout mice lacking this receptor, to model the biological properties of the human receptor. PMID: 21257728
    7. Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response. PMID: 19632227

    显示更多

    收起更多

  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.
  • 数据库链接：

    KEGG: mmu:75863

    STRING: 10090.ENSMUSP00000059574

    UniGene: Mm.109183

Most popular with customers

产品中心
特别关注


X
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |