CYP39A1 Antibody

中文名称：

CYP39A1兔多克隆抗体
货号：

CSB-PA932307
规格：

￥2024
图片：
Western blot analysis of extracts from 293/HeLa cells, using CYP39A1 antibody.
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) CYP39A1 Polyclonal antibody
Uniprot No.：

Q9NYL5
基因名：

CYP39A1
宿主：

Rabbit
反应种属：

Human
免疫原：

Synthesized peptide derived from Internal of Human CYP39A1.
免疫原种属：

Homo sapiens (Human)
克隆类型：

Polyclonal
纯化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度：

It differs from different batches. Please contact us to confirm it.
产品提供形式：

Liquid
应用范围：

ELISA,WB
推荐稀释比：

Application Recommended Dilution

WB 1:500-1:3000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
基因功能参考文献：
1. The CYP39A1 polymorphism rs7761731 may help to identify patients at high risk for treatment related toxicity. PMID: 26475344
2. GSTA1 and CYP39A1 were found to be associated with busulfan clearance. When combined, the two haplotypes explained 17% of the variability in busulfan clearance. PMID: 24192117
亚细胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
蛋白家族：

Cytochrome P450 family
组织特异性：

Liver specific.
数据库链接：

HGNC: 17449

OMIM: 605994

KEGG: hsa:51302

STRING: 9606.ENSP00000275016

UniGene: Hs.387367