COL6A6 Antibody, Biotin conjugated
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中文名称：COL6A6兔多克隆抗体, Biotin偶联
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货号：CSB-PA409861LD01HU
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规格：￥880
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其他：
产品详情
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产品名称：Rabbit anti-Homo sapiens (Human) COL6A6 Polyclonal antibody
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Uniprot No.：
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基因名：
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别名：COL6A6Collagen alpha-6(VI) chain antibody
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宿主：Rabbit
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反应种属：Human
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免疫原：Recombinant Human Collagen alpha-6(VI) chain protein (430-982AA)
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免疫原种属：Homo sapiens (Human)
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标记方式：Biotin
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克隆类型：Polyclonal
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抗体亚型：IgG
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纯化方式：>95%, Protein G purified
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浓度：It differs from different batches. Please contact us to confirm it.
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保存缓冲液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式：Liquid
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应用范围：ELISA
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Protocols：
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储存条件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶点详情
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功能：Collagen VI acts as a cell-binding protein.
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基因功能参考文献：
- Study identified SNPs in COL6A6 associated with atopic dermatitis suggesting that COL6A6 variants may constitute candidate risk factors for early-onset atopic dermatitis. PMID: 28125976
- A whole-exome sequencing approach led to identification of a deletion in RHO through detection of a new linked variant in COL6A6 in autosomal dominant retinitis pigmentosa. PMID: 26321861
- Reduced collagen VI alpha6 chain expression in the skeletal muscle is associated with collagen VI-related myopathies. PMID: 24907562
- The collagen VI alpha6 chain, but not the alpha5 chain, is up-regulated in dystrophic muscles. PMID: 22226732
- collagen VI alpha 6 is an important basal lamina component involved in the regulation of epithelial cell behavior most notably as a regulator of epithelial cell-fibronectin interactions PMID: 21406227
- localization of alpha5, and to a lesser extent alpha6, is restricted to the papillary dermis, where the protein mainly colocalizes with collagen fibrils; both chains were found around blood vessels PMID: 20882040
- The discovery of three additional collagen VI chains doubles the collagen VI family and adds a layer of complexity to collagen VI assembly and function in the extracellular matrix. PMID: 18400749
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亚细胞定位：Secreted, extracellular space, extracellular matrix.
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蛋白家族：Type VI collagen family
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数据库链接：
