CNIH3 Antibody

产品详情

Uniprot No.：

Q8TBE1
基因名：

CNIH3
别名：

CNIH3; Protein cornichon homolog 3; CNIH-3; Cornichon family AMPA receptor auxiliary protein 3
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human CNIH3
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
基因功能参考文献：
1. Study's convergent findings in humans and mice support CNIH3 involvement in the pathophysiology of opioid dependence, complementing prior studies implicating the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate system PMID: 26239289
2. Significant upregulation of CNIH-3 mRNA expression was found in schizophrenia. PMID: 23103966
亚细胞定位：

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
蛋白家族：

Cornichon family
组织特异性：

Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
数据库链接：

HGNC: 26802

KEGG: hsa:149111

STRING: 9606.ENSP00000272133

UniGene: Hs.731723