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CLCA4 Antibody

  • 中文名称:
    CLCA4兔多克隆抗体
  • 货号:
    CSB-PA584850
  • 规格:
    ¥1100
  • 图片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA584850(CLCA4 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

产品详情

  • Uniprot No.:
  • 基因名:
    CLCA4
  • 别名:
    30 kDa form antibody; CaCC-2 antibody; Calcium-activated chloride channel family member 4 antibody; Calcium-activated chloride channel protein 2 antibody; Calcium-activated chloride channel regulator 4 antibody; Clca4 antibody; CLCA4_HUMAN antibody; hCaCC-2 antibody; hCLCA4 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Fusion protein of Human CLCA4
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen affinity purification
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,IHC
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    May be involved in mediating calcium-activated chloride conductance.
  • 基因功能参考文献:
    1. CLCA4 and CLCA2 play complementary but distinct roles in epithelial differentiation PMID: 24386311
    2. CLCA4 modulates the capability to express residual chloride secretion in colonic tissue. PMID: 23073314
    3. CLCA1 and CLCA4 may have roles as modulators of the gastrointestinal basic defect in cystic fibrosis PMID: 15490240
  • 亚细胞定位:
    Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted.
  • 蛋白家族:
    CLCR family
  • 组织特异性:
    Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa.
  • 数据库链接:

    HGNC: 2018

    OMIM: 616857

    KEGG: hsa:22802

    STRING: 9606.ENSP00000359594

    UniGene: Hs.567422