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中文名称:
CDH8兔多克隆抗体
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货号:
CSB-PA697536
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规格:
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图片:
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Western blot analysis of extracts from RAW264.7 cells, using CDH8 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using CDH8 antibody.
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Immunofluorescence analysis of COS7 cells, using CDH8 antibody.
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其他:
产品详情
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产品名称:
Rabbit anti-Homo sapiens (Human) CDH8 Polyclonal antibody
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Uniprot No.:
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基因名:
CDH8
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别名:
CDH8; Cadherin-8
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宿主:
Rabbit
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反应种属:
Human,Mouse,Rat
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免疫原:
Synthesized peptide derived from internal of Human CDH8.
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免疫原种属:
Homo sapiens (Human)
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克隆类型:
Polyclonal
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纯化方式:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:
It differs from different batches. Please contact us to confirm it.
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产品提供形式:
Liquid
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应用范围:
ELISA,WB,IHC,IF
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推荐稀释比:
Application |
Recommended Dilution |
WB |
1:500-1:3000 |
IHC |
1:50-1:100 |
IF |
1:100-1:500 |
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Protocols:
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储存条件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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基因功能参考文献:
- Results show that promoter hypermethylation of ADCY8, CDH8, and ZNF582 are correlated with high-grade squamous intraepithelial lesion. PMID: 27651839
- cadherin 8, a type II neuronal cadherin, is expressed in cyst epithelia both in vivo and in vitro; data suggest that ectopic expression of cadherin 8 in renal epithelial cells is sufficient to cause the morphogenic pattern of cyst formation PMID: 21389276
- Rare familial 16q21 microdeletions and expression analysis implicate CDH8 in susceptibility to autism and learning disabilities. PMID: 20972252
- cadherin-8 may be involved in both kidney morphogenesis as well as tumorigenesis in some types of renal cell carcinoma PMID: 12209956
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亚细胞定位:
Cell membrane; Single-pass type I membrane protein.
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组织特异性:
Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts.
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数据库链接:
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