CC2D1B Antibody

产品详情

Uniprot No.：

Q5T0F9
基因名：

CC2D1B
别名：

CC2D1B antibody; KIAA1836Coiled-coil and C2 domain-containing protein 1B antibody; Five prime repressor element under dual repression-binding protein 2 antibody; FRE under dual repression-binding protein 2 antibody; Freud-2 antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human CC2D1B
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.
基因功能参考文献：
1. CC2D1B regulates degradation and signaling of EGFR and TLR4. PMID: 27769858
2. Human Freud-2/CC2D1B binds to the 5-HT1A dual repressor element and represses the human 5-HT1A receptor gene to regulate its expression in non-serotonergic cells and neurons. PMID: 19423080
3. Paper describes a function of Cc2d1b/Cc2d1a and their Drosophila homologue l(2)gd in D.melanogaster in Notch trafficking. PMID: 17084358
亚细胞定位：

Nucleus.
蛋白家族：

CC2D1 family
组织特异性：

Widely distributed in brain and peripheral tissues.
数据库链接：

HGNC: 29386

KEGG: hsa:200014

STRING: 9606.ENSP00000360642

UniGene: Hs.591451