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B9D2 Antibody

  • 中文名称:
    B9D2兔多克隆抗体
  • 货号:
    CSB-PA861077ESR1HU
  • 规格:
    ¥440
  • 图片:
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA861077ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA861077ESR1HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) B9D2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    B9D2
  • 别名:
    B9D2 antibody; MKSR2B9 domain-containing protein 2 antibody; MKS1-related protein 2 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human B9 domain-containing protein 2 protein (1-175AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity Purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
  • 基因功能参考文献:
    1. The ICIS-1 (Involved in CIlia Stability-1)gene is localized within the TGF-beta1 promoter and is upregulated during mucociliary differentiation. PMID: 17127412
    2. MKS-1 and MKS-1-related proteins 1 and 2 (MKSR-1/EPPB9, MKSR-2/B9D2), localize to transition zones/basal bodies of sensory cilia; subcellular localization is largely co-dependent, pointing to a functional relationship between the proteins PMID: 19208769
    3. ICIS-1 is a new protein associated with ciliated cells and potentially related to cilia stability. This gene is localized within the TGF-beta1 promoter and is ubiquitously expressed in human tissues. PMID: 17127412
  • 相关疾病:
    Meckel syndrome 10 (MKS10)
  • 亚细胞定位:
    Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Nucleus.
  • 蛋白家族:
    B9D family
  • 数据库链接:

    HGNC: 28636

    OMIM: 611951

    KEGG: hsa:80776

    STRING: 9606.ENSP00000243578

    UniGene: Hs.567596