Alpha-conotoxin LvIA Antibody

产品详情

产品名称：

Rabbit anti-Conus lividus (Livid cone) Alpha-conotoxin LvIA Polyclonal antibody
Uniprot No.：

L8BU87
基因名：

Alpha-conotoxin LvIA
别名：

Alpha-conotoxin LvIA (Alpha-CTx LvIA) (Fragment)
宿主：

Rabbit
反应种属：

Conus lividus (Livid cone)
免疫原：

Recombinant Conus lividus (Livid cone) Alpha-conotoxin LvIA protein (21-36aa)
免疫原种属：

Conus lividus (Livid cone)
标记方式：

Non-conjugated
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks alpha-3-beta-2/CHRNA3-CHRNB2 nAChR with high selectivity (IC(50)=8.67 nM (on rat) and 17.5 (on human)). Has also weaker activity on alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) (IC(50)=108 nM (on rat)), alpha-6/alpha-3-beta-4 (CHRNA6/CHRNA3-CHRNB4) (IC(50)=121 nM (on rat)), alpha-3-beta-4 (CHRNA3-CHRNB4) (IC(50)=148 nM (on rat)), and alpha-7/CHRNA7 nAChRs (IC(50)=3000 nM (on rat)). When tested on mouse with hot-plate tests, this toxin significantly increases the base pain threshold and shows analgesic effects.
亚细胞定位：

Secreted.
蛋白家族：

Conotoxin A superfamily
组织特异性：

Expressed by the venom duct.