ASCC2 Antibody

中文名称：

ASCC2兔多克隆抗体
货号：

CSB-PA548485
规格：

￥1100
图片：
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A431 cells, 293T cells, hela cells, Primary antibody: CSB-PA548485(ASCC2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
其他：

产品详情

Uniprot No.：

Q9H1I8
基因名：

ASCC2
别名：

1700011I11Rik antibody; 2610034L15Rik antibody; Activating signal cointegrator 1 complex subunit 2 antibody; AI482016 antibody; ASC 1 complex subunit p100 antibody; ASC-1 complex subunit p100 antibody; ASC1P100 antibody; ASCC 2 antibody; Ascc2 antibody; ASCC2_HUMAN antibody; AW046480 antibody; FLJ21588 antibody; OTTMUSP00000005258 antibody; p100 antibody; RGD1561422 antibody; RP23-280J3.3 antibody; Trip4 complex subunit p100 antibody
宿主：

Rabbit
反应种属：

Human,Mouse
免疫原：

Synthetic peptide of Human ASCC2
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
抗体亚型：

IgG
纯化方式：

Antigen affinity purification
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
产品提供形式：

Liquid
应用范围：

ELISA,WB
推荐稀释比：

Application Recommended Dilution

ELISA 1:2000-1:5000

WB 1:500-1:2000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT) complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes.
亚细胞定位：

Nucleus. Nucleus speckle.
蛋白家族：

ASCC2 family
组织特异性：

Ubiquitous.
数据库链接：

HGNC: 24103

OMIM: 614216

KEGG: hsa:84164

STRING: 9606.ENSP00000305502

UniGene: Hs.731754

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000