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  4. AP1S3 Antibody, Biotin conjugated

AP1S3 Antibody, Biotin conjugated

说明书
  • 中文名称：
    AP1S3兔多克隆抗体, Biotin偶联
  • 货号：
    CSB-PA001868ED01HU
  • 规格：
    ￥1100
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA001868ED01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Human AP1S3 Polyclonal antibody
  • Uniprot No.：
    Q96PC3
  • 基因名：
    AP1S3
  • 别名：
    Adapter-related protein complex 1 subunit sigma-1C antibody; Adaptor protein complex AP 1 sigma 1C subunit antibody; Adaptor protein complex AP-1 subunit sigma-1C antibody; Adaptor related protein complex 1 sigma 3 subunit antibody; AP-1 complex subunit sigma-3 antibody; Ap1s3 antibody; AP1S3_HUMAN antibody; Clathrin assembly protein complex 1 sigma-1C small chain antibody; Golgi adaptor HA1/AP1 adaptin sigma-1C subunit antibody; Sigma 1C subunit of AP-1 clathrin antibody; Sigma-adaptin 1C antibody; Sigma1C-adaptin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human AP-1 complex subunit sigma-3 protein (1-104AA)
  • 免疫原种属：
    Human
  • 标记方式：
    Biotin
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
    ELISA Protocol
    Immunohistochemistry (IHC) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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AP1S3 antibodies

AP1S3 Proteins

靶点详情

  • 功能：
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking.
  • 基因功能参考文献：
    1. study demonstrated that AP1S3 interacts with hepatitis C virus E2 and protects it from proteasome-dependent degradation PMID: 27079945
    2. AP1S3 silencing disrupted the endosomal translocation of the innate pattern-recognition receptor TLR-3 (Toll-like receptor 3) and resulted in a marked inhibition of downstream signaling. PMID: 24791904
  • 相关疾病：
    Psoriasis 15, pustular (PSORS15)
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • 蛋白家族：
    Adaptor complexes small subunit family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 18971

    OMIM: 615781

    KEGG: hsa:130340

    STRING: 9606.ENSP00000379891

    UniGene: Hs.632555

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