AGPS Antibody, HRP conjugated
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中文名称:AGPS兔多克隆抗体, HRP偶联
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货号:CSB-PA001457LB01HU
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) AGPS Polyclonal antibody
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Uniprot No.:
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基因名:
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别名:AAG5 antibody; ADAP-S antibody; ADAS antibody; ADAS_HUMAN antibody; ADHAPS antibody; ADPS antibody; Aging associated gene 5 protein antibody; Aging-associated gene 5 protein antibody; aging-associated protein 5 antibody; AGPS antibody; ALDHPSY antibody; Alkyl-DHAP synthase antibody; Alkyldihydroxyacetonephosphate synthase antibody; Alkyldihydroxyacetonephosphate synthase, peroxisomal antibody; Alkylglycerone phosphate synthase antibody; Alkylglycerone-phosphate synthase antibody; peroxisomal antibody; RCDP3 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Alkyldihydroxyacetonephosphate synthase, peroxisomal protein (279-400AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:HRP
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相关产品
靶点详情
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功能:Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.
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基因功能参考文献:
- we optimized the BITC construction targeting alkylglycerone phosphate synthase (AGPS) by computer-aided design, and the derivants also showed anti-tumor potential in vitro. PMID: 25542233
- AGPS overexpression could be a causation of chemotherapy agent resistance of cancer cells. AGPS silencing could lead to drug uptake and cell cycle arrest and apoptotic cell death. PMID: 24815474
- Results demonstrated that AGPS negatively regulated the invasion potential of glioma and hepatic carcinoma cells by modulating the expression of relevant genes and activity of the MAPK pathway. PMID: 24841318
- AGPS, in addition to maintaining ether lipids, also controls cellular utilization of fatty acids, favoring the generation of signaling lipids necessary for promoting the aggressive features of cancer. PMID: 23980144
- Novel mutations in AGPS (alkylglycerone-phosphate synthase) cause rhizomelic chondrodysplasia punctata (RCDP) type 3. PMID: 21990100
- Defect of ADAPS expression was also assessed by immunoblot PMID: 18571506
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相关疾病:Rhizomelic chondrodysplasia punctata 3 (RCDP3)
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亚细胞定位:Peroxisome membrane. Peroxisome.
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蛋白家族:FAD-binding oxidoreductase/transferase type 4 family
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数据库链接:
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