ABI3 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ABI3 Polyclonal antibody
Uniprot No.：

Q9P2A4
基因名：

ABI3
别名：

ABI3 antibody; NESHABI gene family member 3 antibody; New molecule including SH3 antibody; Nesh antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human ABI gene family member 3 protein (1-366AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May inhibit tumor metastasis. In vitro, reduces cell motility.
基因功能参考文献：
1. Low ABI3 expression is associated with thyroid carcinomas. PMID: 27036019
2. Data show that protein-altering changes are in PLCG2, ABI3, and TREM2 genes highly expressed in microglia and highlight an immune-related protein-protein interaction network in Alzheimer's disease. PMID: 28714976
3. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target. PMID: 21223585
4. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. PMID: 11956071
亚细胞定位：

Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.
蛋白家族：

ABI family
组织特异性：

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
数据库链接：

HGNC: 29859

OMIM: 606363

KEGG: hsa:51225

STRING: 9606.ENSP00000225941

UniGene: Hs.130719