SMAD5 Monoclonal Antibody

SMAD5单克隆抗体（CUSABIO货号：CSB-MA052999）是针对TGF-β信号通路关键调控因子SMAD5开发的科研专用试剂，该靶点通过介导骨形态发生蛋白（BMP）信号传导参与细胞增殖、分化及胚胎发育调控。本产品采用高特异性杂交瘤技术制备，经ELISA、Western Blot（WB）、免疫细胞化学（ICC）及流式细胞术（FC）多平台验证，可精准识别人类、猪、大鼠及小鼠等哺乳动物来源的SMAD5蛋白，适用于肿瘤微环境研究、干细胞定向分化实验及骨骼发育相关机制探索。其优异的种属交叉反应性为跨物种比较研究提供便利，特别适合开展BMP/SMAD信号通路在癌症转移、组织再生修复中的功能解析，以及基因敲除模型验证等实验场景。该抗体在4℃长期储存条件下保持稳定活性，重复实验结果一致性高，是探索TGF-β超家族信号网络调控机制的高效工具。通过优化抗原表位筛选工艺，有效降低非特异性结合干扰，助力研究人员在蛋白质相互作用、亚细胞定位分析等前沿领域获得可靠数据。

mothers against decapentaplegic homolog 5 SMA- and MAD-related protein 5 SMAD, mothers against DPP homolog 5 MAD, mothers against decapentaplegic homolog 5 mothers against decapentaplegic, drosophila, homolog of, 5

Mouse

Human,Pig,Rat,Mouse

Recombinant fragment, corresponding to amino acids 239aa-372aa of Human SMAD5 (C-terminus).

Homo sapiens (Human)

Monoclonal

IgG1

Antigen Affinity Purified

14E2

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB,ICC,FC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol
Flow cytometry (FC) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.