RPA1 Monoclonal Antibody

CUSABIO货号：CSB-MA593248 RPA1单克隆抗体是针对DNA复制与修复关键蛋白RPA1研发的高特异性科研试剂，该抗体可识别人、猴、小鼠及大鼠等多种物种的RPA1蛋白。RPA1作为复制蛋白A复合体的核心亚基，在DNA复制起始、损伤修复及细胞周期检查点调控中发挥重要作用，是研究基因组稳定性、肿瘤发生机制及抗癌药物开发的重要靶标。本产品经严格验证适用于ELISA、Western Blot、免疫细胞化学（ICC）及免疫沉淀（IP）等多种实验体系，其高亲和力特性可精准检测内源性RPA1蛋白的表达水平与亚细胞定位。研究人员可通过该抗体进行DNA损伤应答机制研究、抗癌药物筛选模型的建立，以及肿瘤细胞放射/化学治疗敏感性的分子机制探索，特别适用于研究BRCA1/2突变型肿瘤的合成致死效应。该RPA1抗体为冷冻干燥粉剂，具有优异批次稳定性，搭配专用保存缓冲液可长期维持抗体活性，是开展DNA修复通路研究的可靠工具。

Dmrpa1; Drosophila Replication Protein A; DRPA; HSSB; Human single stranded DNA binding protein; MST075; MSTP075; p70; REPA1; Replication factor A; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit;

Mouse

Human,Monkey,Mouse,Rat

Purified recombinant Human RPA70 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2a

Affinity purified

27B3

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

ELISA,WB,ICC,IP

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200IP:1:200-1:2000

ELISA Protocol
Western Blotting (WB) Protocol
Immunoprecipitation (IP) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.