PDHA1 Monoclonal Antibody

CUSABIO货号：CSB-MA275281 PDHA1单克隆抗体是针对丙酮酸脱氢酶复合体E1α亚基（PDHA1）研发的高特异性科研试剂，该靶点在糖代谢通路中发挥核心作用，通过催化丙酮酸转化为乙酰辅酶A调控细胞能量供应，其表达异常与肿瘤发生、代谢性疾病密切相关。本产品经严格验证可识别人类、小鼠、大鼠、犬及猪等多种物种的PDHA1蛋白，适用于Western Blot、ELISA及免疫细胞化学等实验平台，在细胞能量代谢机制研究、癌症相关信号通路解析以及糖尿病等代谢疾病模型构建中具有重要应用价值。该抗体采用杂交瘤技术制备，具备优异的批间稳定性和抗原结合特异性，能够精准识别天然及变性状态下的靶蛋白，为研究PDHA1在生理病理过程中的分子调控网络提供可靠工具，适用于基础科研领域的蛋白表达分析、亚细胞定位研究及分子互作实验设计。关键词：PDHA1单克隆抗体、丙酮酸脱氢酶、糖代谢研究、Western Blot、免疫细胞化学、能量代谢调控。

pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial PDHE1-A type I pyruvate dehydrogenase complex, E1-alpha polypeptide 1

Mouse

Human,Dog,Rat,Mouse,Pig

Recombinant fragment , corresponding to amino acids 131aa-389aa of Human PDHA1 (C-terminus).

Homo sapiens (Human)

Monoclonal

IgG1

Antigen Affinity Purified

12C9

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.