MMAE&MMAF Monoclonal Antibody

中文名称：

MMAE&MMAF鼠单克隆抗体
货号：

CSB-MA903890I1m
规格：

￥3000
图片：
MMAE&MMAF antibody on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.

The Binding Activity of Disitamab vedotin (Synonyms: RC48) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) at 2 μg/mL can bind Anti-MMAE antibody, the EC₅₀ is 1.908 to 2.492 ng/mL.

The Binding Activity of Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC₅₀ is 1.927 to 3.280 ng/mL.

The Binding Activity of Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC₅₀ is 1.908 to 2.492 ng/mL and 1.927 to 3.280 ng/mL, respectively.
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CUSABIO货号：CSB-MA903890I1m MMAE&MMAF单克隆抗体是针对抗体偶联药物（ADC）中常用细胞毒素成分MMAE（单甲基澳瑞他汀E）和MMAF（单甲基澳瑞他汀F）开发的高特异性科研试剂。该产品采用杂交瘤技术制备，能够精准识别MMAE和MMAF分子结构中的特征表位，在ELISA检测中展现优异的选择性和灵敏度，适用于ADC药物开发过程中有效载荷的定量分析、药物代谢动力学研究及质量控制等科研场景。作为经过严格验证的单克隆抗体，其批间稳定性强、交叉反应性低，可实现对复杂生物样本中MMAE/MMAF分子的准确定量。研究人员可借助该产品建立高重复性的ELISA检测体系，用于评估ADC药物的载药效率、体内外释放动力学及生物分布研究，为优化ADC药物设计提供可靠数据支持。本产品特别适用于从事肿瘤靶向治疗、ADC创新药开发及相关机制研究的科研团队，是探索新型抗癌疗法的重要工具试剂。
基因名：

MMAE; MMAF
别名：

MMAE, Monomethyl auristatin E, SGD-1010, Vedotin; MMAF, Monomethylauristatin F
宿主：

Mouse
反应种属：

Homo sapiens (Human)
免疫原：

MMAE-BSA
标记方式：

Non-conjugated
克隆类型：

Monoclonal
抗体亚型：

IgG2b
纯化方式：

>95%, Protein G purified
克隆号：

25G12B5
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

MMAE&MMAF Monoclonal Antibody

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