MLH1 Monoclonal Antibody

CUSABIO货号：CSB-MA924525 MLH1单克隆抗体是针对DNA错配修复系统核心蛋白MLH1研发的高特异性科研试剂，适用于人源样本的Western Blot和ELISA检测。该抗体采用杂交瘤技术制备，经抗原亲和纯化工艺处理，具有高结合效价（效价值≥1:100,000）和严格验证的特异性，能精准识别约85kDa的MLH1蛋白条带。MLH1作为维持基因组稳定的关键因子，其功能缺失与遗传性Lynch综合征及结直肠癌、子宫内膜癌等恶性肿瘤发生密切相关。本产品可有效支持科研人员在肿瘤发生机制、DNA修复通路研究及错配修复缺陷（dMMR）状态分析等领域的实验需求，特别适用于构建肿瘤细胞模型验证、基因突变相关性研究以及药物靶点筛选等基础科研场景。通过Western Blot可实现组织/细胞裂解液中MLH1蛋白表达水平的定量分析，而ELISA平台则适用于大规模样本筛查中的快速检测，为探索DNA修复机制与肿瘤微环境互作提供可靠工具。

COCA 2; COCA2; DNA mismatch repair protein Mlh1; FCC 2; FCC2; hMLH 1; hMLH1; HNPCC 2; HNPCC; HNPCC2; MGC5172; MLH 1; MLH1; MLH1_HUMAN; MutL homolog 1 (E. coli); MutL homolog 1; MutL homolog 1 colon cancer nonpolyposis type 2;

Mouse

Human

Purified recombinant Human MLH1 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

Affinity purified

29F9

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.

ELISA,WB

Application	Recommended Dilution
WB	1:500-1:5000

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.