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  4. EFHD1 Monoclonal Antibody

EFHD1 Monoclonal Antibody

说明书
  • 中文名称：
    EFHD1鼠单克隆抗体
  • 货号：
    CSB-MA000243
  • 规格：
    ￥1090
  • 图片：
    • IF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100.
    • Western blot analysis of 1) Mouse spleen tissue, 2) Rat spleen tissue, diluted at 1:3000.
  • 其他：

产品详情

  • 产品描述：
    EFHD1单克隆抗体（CUSABIO货号：CSB-MA000243）是针对钙结合蛋白EFHD1开发的高特异性科研试剂，该靶点通过EF-hand结构域参与细胞内钙信号转导，在神经分化过程中呈现显著表达上调特征，对脑发育及肿瘤微环境调控具有重要研究价值。本产品经严格验证适用于人、小鼠、大鼠三物种样本，支持ELISA、Western Blot、免疫组化及免疫荧光四大实验平台，可为神经生物学、肿瘤转移机制等基础研究提供可靠工具。抗体采用100μL标准规格封装，有效期为12个月，经多次质控确保批次稳定性，满足科研场景下蛋白定位、定量分析及组织切片检测等多元化需求，特别适用于探索EFHD1在神经发育调控和肿瘤微环境中的分子作用机制。
  • Uniprot No.：
    Q9BUP0
  • 基因名：
    EFHD1
  • 别名：
    4931430I01Rik antibody; AI452351 antibody; DKFZp781H0842; antibody; EF hand domain containing 1 antibody; EF hand domain family; member D1 antibody; EF-hand domain-containing protein 1 antibody; EF-hand domain-containing protein D1 antibody; EFHD1 antibody; EFHD1_HUMAN antibody; FLJ13612 antibody; MGC103094 antibody; Mitocalcin antibody; MST133 antibody; MSTP133 antibody; PP3051 antibody; RGD1559565 antibody; Swiprosin 2 antibody; Swiprosin-2 antibody; SWS2 antibody
  • 宿主：
    Mouse
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic Peptide
  • 免疫原种属：
    H, M, R
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 克隆号：
    7B5
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:50-1:500
    IF 1:50-1:200
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
    Immunohistochemistry (IHC) Protocol
    Immunofluorescence (IF) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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EFHD1 antibodies

EFHD1 Proteins

靶点详情

  • 功能：
    Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation.
  • 基因功能参考文献：
    1. EFHD1 functions as a novel mitochondrial Ca(2+) sensor underlying Ca(2+)-dependent activation of mitoflashes PMID: 26975899
    2. detection of methylation of PPP1R3C alone or in combination with EFHD1 in plasma DNA showed high sensitivity and specificity in CRC detection, and may be useful detection method for CRC, especially for early-stage CRCs. PMID: 24861485
    3. Cloning of novel mouse genes associated with neuronal function, including Efhd1. PMID: 12270117
  • 亚细胞定位：
    Mitochondrion inner membrane.
  • 数据库链接：

    HGNC: 29556

    OMIM: 611617

    KEGG: hsa:80303

    STRING: 9606.ENSP00000264059

    UniGene: Hs.516769

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