DM1&DM4 Monoclonal Antibody
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中文名称:DM1&DM4 Monoclonal Antibody
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货号:CSB-MA989811I3m
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规格:¥3000
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图片:
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The Binding Activity of Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) with Anti-DM1&DM4 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) at 2 μg/mL can bind Anti-DM1&DM4 antibody, the EC50 is 3.686 to 4.819 ng/mL and 3.038 to 4.195 ng/mL, respectively.
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其他:
产品详情
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产品描述:CUSABIO货号:CSB-MA989811I3m DM1&DM4单克隆抗体是针对抗体药物偶联物(ADC)中关键细胞毒性成分美登素衍生物DM1/DM4开发的高特异性科研试剂。该抗体通过杂交瘤技术制备,经严格验证可在ELISA平台上实现对Human样本中DM1和DM4分子的精准检测,为ADC药物的作用机制研究和疗效评估提供可靠工具。作为抗体药物开发领域的重要检测工具,本产品具有高度特异性识别能力,能够有效区分DM1和DM4的结构差异,适用于ADC药物研发过程中有效载荷的定量分析、药物代谢动力学研究以及生物样本中游离型细胞毒素的检测。实验验证显示其在ELISA体系中表现稳定,可满足不同浓度梯度的检测需求,为肿瘤治疗领域的科研人员提供关键的DM1/DM4检测解决方案。该产品严格限定于科学研究用途,是探索ADC药物作用机理、优化药物偶联工艺及评估药物安全性的理想选择,相关关键词:DM1/DM4检测抗体、ADC药物研究试剂、美登素特异性抗体、ELISA检测试剂、抗体药物开发工具。
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基因名:DM1&DM4
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别名:DM1, DM4, Mertansine, Maytansinoid DM1
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宿主:Mouse
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反应种属:Homo sapiens (Human)
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免疫原:DM4-BSA
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标记方式:Non-conjugated
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克隆类型:Monoclonal
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抗体亚型:IgG2a
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纯化方式:>95%, Protein G purified
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克隆号:13F3F9
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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