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DM1&DM4 Monoclonal Antibody

  • 中文名称:
    DM1&DM4 Monoclonal Antibody
  • 货号:
    CSB-MA989811I3m
  • 规格:
    ¥3000
  • 图片:
    • The Binding Activity of Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) with Anti-DM1&DM4 antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) at 2 μg/mL can bind Anti-DM1&DM4 antibody, the EC50 is 3.686 to 4.819 ng/mL and 3.038 to 4.195 ng/mL, respectively.
  • 其他:

产品详情

  • 产品描述:
    CUSABIO货号:CSB-MA989811I3m DM1&DM4单克隆抗体是针对抗体药物偶联物(ADC)中关键细胞毒性成分美登素衍生物DM1/DM4开发的高特异性科研试剂。该抗体通过杂交瘤技术制备,经严格验证可在ELISA平台上实现对Human样本中DM1和DM4分子的精准检测,为ADC药物的作用机制研究和疗效评估提供可靠工具。作为抗体药物开发领域的重要检测工具,本产品具有高度特异性识别能力,能够有效区分DM1和DM4的结构差异,适用于ADC药物研发过程中有效载荷的定量分析、药物代谢动力学研究以及生物样本中游离型细胞毒素的检测。实验验证显示其在ELISA体系中表现稳定,可满足不同浓度梯度的检测需求,为肿瘤治疗领域的科研人员提供关键的DM1/DM4检测解决方案。该产品严格限定于科学研究用途,是探索ADC药物作用机理、优化药物偶联工艺及评估药物安全性的理想选择,相关关键词:DM1/DM4检测抗体、ADC药物研究试剂、美登素特异性抗体、ELISA检测试剂、抗体药物开发工具。
  • 基因名:
    DM1&DM4
  • 别名:
    DM1, DM4, Mertansine, Maytansinoid DM1
  • 宿主:
    Mouse
  • 反应种属:
    Homo sapiens (Human)
  • 免疫原:
    DM4-BSA
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    IgG2a
  • 纯化方式:
    >95%, Protein G purified
  • 克隆号:
    13F3F9
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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