CYP17A1 Monoclonal Antibody

本产品为针对人源CYP17A1靶点研发的高特异性单克隆抗体（CUSABIO货号：CSB-MA905936），适用于ELISA和Western Blot（WB）等经典免疫检测实验。CYP17A1作为细胞色素P450超家族成员，是类固醇激素生物合成的关键酶，催化孕烯醇酮和孕酮转化为雄激素前体，其异常表达与前列腺癌、乳腺癌等激素依赖性肿瘤的发生发展密切相关。该抗体基于杂交瘤技术制备，经严格验证可精准识别天然构象的CYP17A1蛋白，适用于人类样本中该靶点蛋白的定性与半定量检测，为内分泌调控机制研究、肿瘤代谢通路探索以及相关药物靶点开发提供可靠工具。科研人员可将其应用于体外培养细胞、组织裂解液等实验体系，结合ELISA技术进行高通量筛选，或通过WB实验验证CYP17A1在特定生理病理状态下的表达水平变化，助力生殖内分泌学、肿瘤分子生物学等领域的机理研究。本产品经多批次质控确保批次稳定性，实验方案兼容常规检测条件，是开展CYP17A1蛋白功能研究的优选试剂。

20 lyase; CP17A_HUMAN; CPT7; CYP17; CYP17A1; CYPXVII; Cytochrome P450 17A1; Cytochrome P450 family 17; Cytochrome P450 family 17 subfamily A polypeptide 1; Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia;

Mouse

Human

Purified recombinant Human CYP17A1 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

10D5

It differs from different batches. Please contact us to confirm it.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

ELISA,WB

Application	Recommended Dilution
WB	1:500-1:5000

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.