CHD4 Monoclonal Antibody

CUSABIO货号：CSB-MA109780 CHD4单克隆抗体是针对染色质重塑关键调控因子CHD4研发的高特异性科研试剂，该靶蛋白作为Mi-2/NuRD复合体的核心亚基，在DNA损伤修复、干细胞分化及表观遗传调控中发挥重要作用，其功能异常与多种肿瘤发生及神经系统疾病密切相关。本产品采用杂交瘤技术制备，经ELISA、Western Blot和免疫沉淀（IP）三大实验平台严格验证，在人类样本中展现出优异的抗原识别能力，适用于染色质互作研究、蛋白质复合体分离鉴定及基因表达调控机制解析等前沿领域。通过高纯度重组蛋白免疫制备的抗体具备高亲和力与低交叉反应特性，特别适用于研究肿瘤微环境中染色质动态重塑、胚胎发育过程中的表观遗传调控，以及DNA损伤修复通路相关分子机制等科研场景。该抗体为冷冻液体剂型，建议配合常规抗体保存及使用方法开展染色质免疫共沉淀测序（ChIP-seq）、蛋白质相互作用网络分析等实验，为表观遗传学、癌症生物学及神经退行性疾病研究提供可靠工具。

ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta;

Mouse

Human

Purified recombinant Human CHD4 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

Affinity purified

12C5

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.

ELISA,WB,IP

Application	Recommended Dilution
WB	1:500-1:5000
IP	1:200-1:2000

ELISA Protocol
Western Blotting (WB) Protocol
Immunoprecipitation (IP) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.