Your Good Partner in Biology Research

中文简体

CSF2｜ CTLA4｜ DLL3｜ EGFR｜ IL4｜ IL4R｜ LAG3｜ MSTN｜ NECTIN4｜ NT5E｜ SEZ6｜ TM4SF1｜ TNFSF13｜ TPO

  1. Home
  2. 抗体
  3. 单克隆抗体
  4. AGBL2 Monoclonal Antibody

AGBL2 Monoclonal Antibody

说明书
  • 中文名称：
    AGBL2鼠单克隆抗体
  • 货号：
    CSB-MA732978A0m
  • 规格：
    ￥1320
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, PC-3 whole cell lysate
      All lanes: AGBL2 antibody at 1:1000
      Secondary
      Goat polyclonal to mouse IgG at 1/50000 dilution
      Predicted band size: 32 KDa
      Observed band size: 32, 49, 104 KDa
      Exposure time：5min
  • 其他：

产品详情

  • 产品描述：
    CUSABIO货号：CSB-MA732978A0m AGBL2单克隆抗体是针对人源AGBL2（ATP/GTP结合蛋白样2）靶点研发的高特异性科研试剂，该蛋白作为胞内羧肽酶家族成员，在蛋白质翻译后修饰及细胞信号调控中发挥重要作用，其异常表达与多种生理病理过程相关。本产品经Western Blot（WB）和ELISA双平台验证，采用杂交瘤技术制备，具有明确的IgG亚型鉴定及严格的亲和纯化工艺，确保批次间高一致性。在肿瘤微环境研究、神经退行性疾病机制探索等科研场景中，该抗体可精准识别内源性AGBL2蛋白，助力研究者解析其在不同细胞模型或组织样本中的表达分布规律及功能调控网络。作为经多实验体系验证的可靠工具，本品适用于蛋白互作研究、信号通路图谱构建及疾病相关生物标志物筛选等基础研究领域，为精准医学研究提供关键技术支持。
  • 产品名称：
    Mouse anti-Homo sapiens (Human) AGBL2 Monoclonal Antibody antibody
  • Uniprot No.：
    Q5U5Z8
  • 基因名：
    AGBL2
  • 别名：
    AGBL 2 antibody; AGBL2 antibody; ATP/GTP binding protein like 2 antibody; ATP/GTP-binding protein-like 2 antibody; Carboxypeptidase 2 cytosolic antibody; CBPC2_HUMAN antibody; CCP2 antibody; Cytosolic carboxypeptidase 2 antibody; FLJ23598 antibody
  • 宿主：
    Mouse
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Cytosolic carboxypeptidase 2 protein (10-270AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Monoclonal Antibody
  • 抗体亚型：
    IgG2b
  • 纯化方式：
    Affinity purification
  • 克隆号：
    1F3C12
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

相关产品

AGBL2 antibodies

AGBL2 Proteins

靶点详情

  • 功能：
    Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
  • 基因功能参考文献：
    1. Findings suggest that ATP/GTP binding protein like 2 (AGBL2) plays a critical oncogenic role in the pathogenesis of hepatocellular carcinoma (HCC) through modulation on immunity-related GTPase family, M protein (IRGM)-regulated autophagy and aurora kinase A (Aurora A) activity. PMID: 29126912
    2. Suggest role for AGBL2 in cell proliferation and chemotherapy resistance in gastric cancer. PMID: 25916089
    3. High AGBL2 expression is associated with breast cancer. PMID: 24884516
    4. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY-bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis. PMID: 21303978
  • 亚细胞定位：
    Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Peptidase M14 family
  • 数据库链接：

    HGNC: 26296

    OMIM: 617345

    KEGG: hsa:79841

    STRING: 9606.ENSP00000298861

    UniGene: Hs.147377

Most popular with customers

产品中心
特别关注


X
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |