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中文名称：绵羊卵泡刺激素(FSH)酶联免疫试剂盒
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货号：CSB-E13170Sh
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规格：96T/48T
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价格：￥3600/￥2500
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其他：
产品详情
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产品描述：本试剂盒为绵羊卵泡刺激素（FSH）的定量检测而设计，采用双抗体夹心法原理，可精准测定生物样本中FSH的浓度。FSH作为垂体前叶分泌的关键糖蛋白激素，在哺乳动物生殖调控中发挥核心作用，通过促进卵泡发育、调控雌激素分泌及支持精子生成参与生殖生理过程。试剂盒包含预包被特异性抗体的96孔板、标准品、检测抗体及HRP标记物，操作流程仅需4.5小时，包含1.5小时孵育和30分钟显色步骤，具有高灵敏度和特异性，标准曲线范围覆盖常规生理浓度（具体检测范围需参照说明书），适用于血清、血浆等样本分析。该产品为生殖生物学研究提供可靠工具，可用于探究繁殖周期调控机制、评估动物繁殖力、监测内分泌功能异常等科研场景，同时支持畜牧业中优良种畜的选育研究。试剂盒组分需按说明书要求于-20℃或2-8℃保存，避免反复冻融。货号CSB-E13170Sh，适用于需要高重复性数据的体外实验研究。
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别名：FSHBFollitropin subunit beta ELISA kit; Follicle-stimulating hormone beta subunit ELISA kit; FSH-B ELISA kit; FSH-beta ELISA kit; Follitropin beta chain ELISA kit
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缩写：FSH
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Uniprot No.：
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种属：Ovis aries (Sheep)
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Signal Transduction
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测定原理：quantitative
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测定方法：Sandwich
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精密度：
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线性度：
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回收率：
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标准曲线：
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数据处理：
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货期：3-5 working days
引用文献
- Dose-dependent effects of luteinizing hormone and follicle stimulating hormone on in vitro maturation, apoptosis, secretion function and expression of follicle Wei, S.et al,South African Journal of Animal Science,2018
- Annual Change of Reproductive Hormones in Female Angora Goats Erkan Pehlivan.et al,,2022
- Effect of immunization against GnRH on hypothalamic and testicular function in rams Han X.et al,Theriogenology,2015
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靶点详情
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功能：Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
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基因功能参考文献：
- A novel GnRH response element between -750 bp and -232 bp of the ovine FSHB promoter. PMID: 23874399
- Data suggest that dietary components (phytoestrogens here) down-regulate basal secretion/total FSH (CGA+FSHB) production yet up-regulate gonadotropin-releasing hormone agonist-induced luteinizing hormone (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
- In ewes, infusion with genistein decreased the level FSH-beta in the adenohypophysis. PMID: 15531133
- Activation of TAK1 (and probably p38-MAPK), but not Smad3, is necessary for triggering induction of oFSHbeta by activin. PMID: 16081641
- Activin gathers Smads and Smad-associated proteins at the promoter region to regulate expression of the ovine FSHB and overall follitropin production. PMID: 17584958
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亚细胞定位：Secreted.
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蛋白家族：Glycoprotein hormones subunit beta family
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数据库链接：
KEGG: oas:443387
UniGene: Oar.430
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