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中文名称：羊促肾上皮质激素释放激素(CRH)酶联免疫试剂盒
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货号：CSB-EL005963SH
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规格：96T/48T
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价格：￥4200/￥3000
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其他：
产品详情
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产品描述：羊促肾上皮质激素释放激素(CRH)酶联免疫试剂盒（CSB-EL005963SH）为竞争法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的CRH含量。CRH即促肾上腺皮质激素释放激素，它在应激反应调节中起核心作用，参与调控神经内分泌、免疫系统等。研究机制上，主要通过与特定受体结合，激活相关信号通路，影响下游激素分泌，还和情绪、记忆等神经活动有密切联系，在神经精神疾病研究中受关注。试剂盒检测范围为14 pg/mL-500 pg/mL，该产品适用于神经内分泌研究、应激相关疾病机制探索、动物模型中的HPA轴功能评估等科研领域，支持研究人员通过血清、血浆或组织样本分析CRH的动态变化，为神经科学、内分泌学及行为学等基础研究提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：CRHCorticoliberin ELISA Kit; Corticotropin-releasing factor ELISA Kit; CRF ELISA Kit; Corticotropin-releasing hormone ELISA Kit; Endorpholiberin ELISA Kit
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缩写：CRH
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Uniprot No.：
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种属：Ovis aries (Sheep)
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样本类型：serum, plasma, tissue homogenates
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检测范围：14 pg/mL-500 pg/mL
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灵敏度：14 pg/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Neuroscience
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测定原理：quantitative
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测定方法：Competitive
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数据处理：
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货期：3-5 working days
引用文献
- Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions T Misztal,Theriogenology,2021
- Temporal changes in the cerebrospinal fluid allopregnanolone concentration and hypothalamic-pituitary-adrenal axis activity in sheep during pregnancy and early lactation Tomasz Misztal, et al,Livestock Science,2019
- Allopregnanolone reduces neuroendocrine response to acute stressful stimuli in sheep Misztal T, et al,Journal of Endocrinology,2019
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靶点详情
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功能：Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.
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亚细胞定位：Secreted.
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蛋白家族：Sauvagine/corticotropin-releasing factor/urotensin I family
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组织特异性：Produced by the hypothalamus.
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