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Rat hepatic lipase,HL ELISA Kit

  • 中文名称:
    大鼠肝脂酶(HL)酶联免疫试剂盒
  • 货号:
    CSB-E10032r
  • 规格:
    96T/48T
  • 价格:
    ¥3900/¥2500
  • 其他:

产品详情

  • 产品描述:
    大鼠肝脂酶(HL)酶联免疫试剂盒(CSB-E10032r)为竞争法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的LIPC含量。LIPC即肝脂酶,是血浆脂蛋白代谢关键酶。其背景上参与调节高密度脂蛋白胆固醇代谢等。研究机制方面,主要通过水解甘油三酯和磷脂来调节脂蛋白颗粒大小和组成,影响胆固醇逆向转运,与心血管疾病等的发生发展密切相关。试剂盒检测范围为15.6 pg/mL-1000 pg/mL,可应用于肝脏代谢功能研究、脂质代谢调控机制探索、药物或营养干预对HL表达影响的评估等科研场景,尤其适用于心血管疾病、肥胖症等代谢相关疾病的动物模型研究,为体外实验提供高灵敏度的检测方案。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
  • 别名:
    LipcHepatic triacylglycerol lipase ELISA Kit; HL ELISA Kit; Hepatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit; Lipase member C ELISA Kit
  • 缩写:
  • Uniprot No.:
  • 种属:
    Rattus norvegicus (Rat)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    15.6 pg/mL-1000 pg/mL
  • 灵敏度:
    3.9 pg/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Metabolism
  • 测定原理:
    quantitative
  • 测定方法:
    Competitive
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 功能:
    Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position.
  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    AB hydrolase superfamily, Lipase family
  • 数据库链接: