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中文名称:大鼠脂联素(ADP)酶联免疫试剂盒
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货号:CSB-E07271r
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规格:96T/48T
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价格:¥3900/¥2500
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其他:
产品详情
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产品描述:CUSABIO大鼠脂联素(ADP)酶联免疫检测试剂盒(货号:CSB-E07271r),基于双抗体夹心法原理实现定量检测,可精准分析血清、血浆、细胞培养上清液及组织匀浆样本中的脂联素水平,检测灵敏度达0.156 ng/mL,线性范围为0.156-10 ng/mL。脂联素作为脂肪细胞分泌的重要激素蛋白,在调节糖脂代谢平衡、增强胰岛素敏感性及抗炎过程中发挥关键作用,其表达水平与肥胖、2型糖尿病及心血管疾病等代谢综合征密切相关。CUSABIO试剂盒采用高特异性捕获抗体和检测抗体组合,通过酶标信号放大系统实现目标蛋白的定量分析,适用于代谢调控机制研究、药物干预效果评估或疾病模型构建等科研领域,为探索脂联素在能量代谢、炎症反应及胰岛素抵抗中的作用提供可靠工具。该产品仅限科学研究使用。
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缩写:ADP
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, cell culture supernates, tissue homogenates
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检测范围:0.156 ng/mL-10 ng/mL
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灵敏度:0.039 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cardiovascular
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测定原理:quantitative
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测定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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线性度:
To assess the linearity of the assay, samples were spiked with hig3h concentrations of rat ADP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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数据处理:
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货期:3-5 working days
引用文献
- The effect of adipose-derived mesenchymal stem cells against high fructose diet induced liver dysfunction and dysbiosis MA Mohammed, NHA Hay, MT Mohammed,Naunyn-Schmiedeberg's Archives of Pharmacology,2024
- Unraveling the hepatic stellate cells mediated mechanisms in aging's influence on liver fibrosis RM Wahid,Scientific reports,2024
- Regulation and Role of Adiponectin Secretion in Rat Ovarian Granulosa Cells Y Zhou,International Journal of Molecular Sciences,2024
- The ameliorative role of germinated fenugreek and barley grains on the structure and function of offspring's tibialis muscle maternally fed on high fat diet FA Hassan Megahed,/,2024
- The Potential Efficacy of Artemisia Anuua L. Extract Nanoparticles in Mitigating Obesity-Related-Metabolic Complications in Hypercaloric Diet-Fed Rats MM Mohameda,/,2023
- The potential efficacy of Artemisia anuua L. extract nanoparticles in mitigating obesity-related-metabolic complications in hypercaloric diet-fed rats MM Mohamed,/,2024
- A novel role of FSH on regulating ovarian adiponectin expression in rat ovarian granulosa cells Y Zhou,researchsquare,2023
- Enhancement of biochemical and genomic pathways through lycopene-loaded nano-liposomes: Alleviating insulin resistance, hepatic steatosis, and autophagy in obese rats with non-alcoholic fatty liver disease: Involvement of SMO, GLI-1, and PTCH-1 genes GA Salem,Gene,2023
- Quinoa and Chia Modulate AMPK/PPAR-ɣ Signaling in High-Fat Diet–Induced Obesity Rat Model NH Omran,Revista Brasileira de Farmacognosia,2023
- Cytokine modulation by etanercept ameliorates metabolic syndrome and its related complications induced in rats administered a high-fat high-fructose diet NF Hassan,Scientific reports,2022
- Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats MM Samaha,Antioxidants (Basel, Switzerland),2022
- Diacerein versus adipoRon as adiponectin modulators in experimentally-induced end-stage type 2 diabetes mellitus in rats MM Samaha,Environmental toxicology and pharmacology,2022
- Saponin-rich extract of Tribulus terrestris alleviates systemic inflammation and insulin resistance in dietary obese female rats: Impact on adipokine/hormonal disturbances YousraAbdel-Mottaleb,Biomedicine & pharmacotherapy,2022
- The metabolic impact and beneficial effects of different energy restriction protocols in rats: an alternative health plan K El-Dawy,Journal of Animal Health and Production,2021
- Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and interscapular brown adipose tissue of obese rats Q Cao,FASEB J,2020
- Beneficial phytoestrogenic effects of resveratrol on polycystic ovary syndromein rat model N Zhang,Journal Gynecological Endocrinology,2020
- Alagebrium Mitigates Metabolic Insults in High Carbohydrate and High Fat Diet Fed Wistar Rats S Hassan,Pharmaceutical Sciences,2020
- Anti-depressive effects of Kai-Xin-San on lipid metabolism in depressed patients and CUMS rats using metabolomic analysis X Zhou,Journal of Ethnopharmacology,2020
- Lansoprazole enhances the antidiabetic effect of dapagliflozin in fortified diet┸\fed streptozotocin┸\treated diabetic rats Noha M. Gamil,J. Biochem. Mol. Toxicol,2020
- Experimental hypothyroidism in adult male rats: the effects of Artemisia dracunculus aqueous extract on serum thyroid hormones, lipid profile, leptin, adiponectin, and antioxidant factors Mohammadi M M, et al,Comparative Clinical Pathology,2019
- Alagebrium Mitigates Metabolic Insults in High Carbohydrate High Fat Diet Fed Rats Hady S H A, et al,Pharmaceutical Sciences,2019
- Grinding levels of raspberry pomace affect intestinal microbial activity, lipid and glucose metabolism in Wistar rats BartoszFotschk, et al,Food research international,2019
- Alpha lipoic acid protects against dexamethasone-induced metabolic abnormalities via APPL1 and PGC-1 α up regulation Mohammed MA, et al,Steroids,2019
- High Fat/High Glucose Diet Induces Metabolic Syndrome in an Experimental Rat Model Moreno-Fernandez S.et al,Nutrients,2018
- Protective Effects of Ellagitannin-Rich Strawberry Extracts on Biochemical and Metabolic Disturbances in Rats Fed a Diet High in Fructose Bartosz Fotschki .et al,Nutrients,2018
- A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota Zhao L.et al,Food Funct.,2017
- Tetradecyl 2,3-Dihydroxybenzoate Improves the Symptoms of Diabetic Mice by Modulation of Insulin and Adiponectin Signaling Pathways Lan Xiang.et al,Front. Pharmacol,2017
- Pepsin egg white hydrolysate ameliorates metabolic syndrome in high-fat/high-dextrose fed rats Silvia Moreno-Fernndez.et al,Food & Function,2017
- Anti-diabetic effects of soluble and insoluble dietary fibre from deoiled cumin in low-dose streptozotocin and high glucose-fat diet-induced type 2 diabetic rats Ma M.et al, Journal of Functional Foods,2016
- Glycyrrhizic acid prevents high calorie diet-induced metabolic aberrations despite the suppression of peroxisome proliferator-activated receptor 纬 expression Hong Sheng Cheng.et al,Nutrition,2016
- Fish oil supplementation alleviates depressant-like behaviors and modulates lipid profiles in rats exposed to chronic unpredictable mild stress Tang M.et al,BMC Complement Altern Med.,2015
- Comparison of the anti-obesity and hypocholesterolaemic effects of single Lactobacillus casei strain Shirota and probiotic cocktail Shafiq Aazmi et al,Food Science & Technology,2015
- CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and production of pathogenic IgG-antibodies Dennis Wolf et al,PLOS ONE,2012
靶点详情
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最新研究进展:近年来,脂联素(Adiponectin,ADP)作为一种由脂肪组织分泌的激素,受到了广泛关注。ADP对人体的代谢、炎症反应和心血管健康等生理过程均具有重要的作用。最新的研究发现,ADP在以下几个方面具有突出的研究进展:代谢调节:研究表明,ADP可以调节人体的葡萄糖代谢和脂质代谢,降低胰岛素抵抗和脂肪肝的发生,对代谢综合征和肥胖等代谢性疾病的治疗具有潜在作用。炎症调节:ADP也在炎症反应中发挥重要作用。研究发现,ADP可以抑制炎症介质的产生和释放,调节免疫细胞的活化和凋亡,对于炎症反应和自身免疫性疾病的治疗具有一定的潜力。心血管保护:ADP能够降低血压和血脂,预防动脉粥样硬化和心血管疾病的发生。此外,ADP还能够减轻心肌损伤和缺血再灌注损伤。肿瘤治疗:ADP在肿瘤治疗中也备受关注。研究发现,ADP可以影响肿瘤细胞的增殖、侵袭和转移,对于肿瘤的治疗和预防具有潜在作用。总之,ADP作为一种重要的激素,其在代谢、炎症、心血管和肿瘤等多个生理和病理过程中的作用引起了广泛关注,对于相关疾病的治疗和预防具有重要的临床应用前景。
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