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中文名称：大鼠L选择素(L-Selectin/CD62L)酶联免疫试剂盒
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货号：CSB-E07431r
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规格：96T/48T
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价格：￥3900/￥2500
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其他：
产品详情
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产品描述：CUSABIO专为大鼠样本设计的L选择素（CD62L）定量检测试剂盒，适用于血清、血浆及组织匀浆样本的精准分析，检测灵敏度覆盖78.125-5000 pg/mL的宽动态范围。L选择素作为细胞黏附分子家族成员，在白细胞迁移及炎症反应初期调控中发挥关键作用，其表达水平与免疫细胞活化和炎症进程密切相关。该试剂盒采用双抗体夹心技术原理，通过预包被高特异性抗体捕获目标蛋白，结合辣根过氧化物酶标记检测抗体实现信号放大，实验全程可在4.5小时内完成，标准曲线R²值稳定高于0.99，确保数据可靠性。科研人员可借助本试剂盒开展免疫调控机制、炎症性疾病模型评价或药物干预研究，例如在实验性自身免疫疾病、感染模型或组织损伤修复等研究中定量分析L选择素动态变化，为探索白细胞迁移相关分子机制提供高灵敏度工具。试剂盒包含优化后的预混缓冲液及标准品，支持96孔板多次检测，适配常规实验室设备操作流程。
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别名：Sell; Lnhr; Ly-22; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; CD antigen CD62L
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缩写：
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Uniprot No.：
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种属：Rattus norvegicus (Rat)
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样本类型：serum, plasma, tissue homogenates
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检测范围：78.125 pg/mL-5000 pg/mL
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灵敏度：64 pg/mL
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Stem Cells
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测定原理：quantitative
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测定方法：Sandwich
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数据处理：
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货期：3-5 working days
引用文献
- Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "Composite" Blast Stanislav I. Svetlov et al,Frontiers in Neurology,2012
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靶点详情
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功能：Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
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亚细胞定位：Cell membrane; Single-pass type I membrane protein.
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蛋白家族：Selectin/LECAM family
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组织特异性：Expressed in peripheral blood mononuclear cells (PBMC), spleen and thymus.
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数据库链接：
STRING: 10116.ENSRNOP00000003733
UniGene: Rn.10461
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