Rat Alpha-1-antitrypsin(SERPINA1) ELISA kit
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中文名称:大鼠α1-抗胰蛋白酶(SERPINA1)酶联免疫试剂盒
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货号:CSB-EL021053RA
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:大鼠α1-抗胰蛋白酶(SERPINA1)酶联免疫试剂盒(CSB-EL021053RA)为竞争法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的SERPINA1含量。SERPINA1是重要靶点,其编码的α1 - 抗胰蛋白酶可抑制多种蛋白酶活性。研究发现它与肺部疾病、肝脏疾病等密切相关,机制可能是其异常导致蛋白酶 - 抗蛋白酶失衡,引发组织损伤,目前围绕它的治疗研究在积极开展。试剂盒检测范围为62.5 ng/mL-4000 ng/mL,适用于科研领域中对肝脏功能、炎症反应或代谢异常相关机制的研究,例如肝损伤模型评估、蛋白酶 - 抗蛋白酶系统平衡分析,以及药物干预实验中的生物标志物检测,为相关基础研究和生物医学探索提供可靠工具。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
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别名:Serpina1Alpha-1-antiproteinase ELISA kit; Alpha-1-antitrypsin ELISA kit; Alpha-1-proteinase inhibitor ELISA kit; Serpin A1 ELISA kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates
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检测范围:62.5 ng/mL-4000 ng/mL
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灵敏度:15.6 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cardiovascular
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测定原理:quantitative
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测定方法:Competitive
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数据处理:
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货期:3-5 working days
相关产品
靶点详情
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功能:Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.
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基因功能参考文献:
- A1AT bidirectional uptake and secretion from lung endothelial cells towards the alveolar epithelium and airspaces PMID: 24743137
- These results suggest that transfer of the N-terminal acidic extension of HCII to alpha1-PI M358R enhanced its inhibition of thrombin by conferring the ability to bind exosite 1 on HAPI M358R. PMID: 16981704
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亚细胞定位:Secreted.
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蛋白家族:Serpin family
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组织特异性:Plasma.
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数据库链接:
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