Mouse ovalbumin specific IgE,OVA sIgE ELISA Kit

中文名称：

小鼠卵清蛋白特异性IgE(OVA sIgE)酶联免疫试剂盒
货号：

CSB-E08914m
规格：

96T/48T
价格：

￥3800/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

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产品描述：

小鼠卵清蛋白特异性IgE(OVA sIgE)酶联免疫试剂盒（CSB-E08914m）为间接法ELISA试剂盒，定性检测血清、血浆样本中的OVA sIgE含量。OVA sIgE即卵清蛋白特异性免疫球蛋白E，是一种针对卵清蛋白的特异性抗体。其背景与过敏反应相关，在机体接触卵清蛋白后产生。研究机制方面，它可介导肥大细胞和嗜碱性粒细胞释放炎症介质，引发一系列过敏症状。对其研究有助于深入了解过敏发病机制。该产品适用于科研场景中过敏动物模型构建、免疫应答机制研究、抗过敏药物筛选及疫苗效果评价等领域，为探索Th2型免疫反应及过敏原交叉反应提供实验支持本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：

N/A
缩写：

OVA sIgE
种属：

Mus musculus (Mouse)
样本类型：

serum, plasma
检测范围：

Request Information
灵敏度：

Request Information
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Others
测定原理：

qualitative
测定方法：

Indirect

精密度：

Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.

标准曲线：

Test parameter
specification
test result
Positive control
>0.8
1.506
Negative control
<0.2
0.176
Positive rate
10，Positive
100%
Negative rate
10，Negative
100%
货期：

3-5 working days

引用文献

Combining Network Pharmacology and Transcriptomics to Investigate the Mechanisms of Yujiang Paidu Decoction in the Treatment of Chronic Rhinosinusitis with Nasal Polyps Y Li, Y Yin, J Xiong, Z Zhang, L Li, B Zhang,Drug Design, Development and Therapy,2024
Melatonin regulates circadian clock proteins expression in allergic airway inflammation SN Guo,Heliyon,2024
Lactobacillus rhamnosus Probio-M9 alleviate OVA-sensitized food allergy through modulating gut microbiota and its metabolism J Shi,Food & function,2023
Establishment of different experimental asthma models in mice Yu QL,Experimental and therapeutic medicine,2023
Untargeted Metabolomic Profiling Reveals Changes in Gut Microbiota and Mechanisms of Its Regulation of Allergy in OVA-Sensitive BALB/c Mice J Xu,Journal of Agricultural and Food Chemistry,2023
Apolipoprotein AI inhibited group II innate lymphoid cell response mediated by microRNA-155 in allergic rhinitis A Longobardi,The journal of allergy and clinical immunology. Global,2024
TLR2-hif1α-mediated glycolysis contributes to pyroptosis and oxidative stress in allergic airway inflammation JF Sha,Free radical biology & medicine,2023
Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation QM Xie,Antioxidants,2023
Nebulized Mycobacterium vaccae protects against asthma by attenuating the imbalance of IRF4/IRF8 expression in dendritic cells QX Sun,Asian Pacific Journal of Tropical Biomedicine,2022
MicroRNA-223-3p regulates allergic inﬂammation by targeting INPP4A Y Zhou,Brazilian Journal of Otorhinolaryngology,2020
Establishing a high microbial load maternal-offspring asthma model in adult mice Y Li,Int. Immunopharmacol,2020
Bifidobacterium infantis Relieves Allergic Asthma in Mice by Regulating Th1/Th2 W Wang,Med. Sci. Monit,2020
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7 Lou L,Biomed Pharmacother,2019
Particulate matters induce acute exacerbation of allergic airway inflammation via the TLR2/NF-κB/NLRP3 signaling pathway Dai M Y, et al,Toxicology Letters,2019
Maternal 1-nitropyrene exposure during pregnancy increases susceptibility of allergic asthma in adolescent offspring Xue Lu, et al,Chemosphere,2019
Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation Yunxiang Lv,Journal of Immunology Research,2019
Sevoflurane Prevents Airway Remodeling via Downregulation of VEGF and TGF-β1 in Mice with OVA-Induced Chronic Airway Inflammation Shen QY, et al,Inflammation,2019
MTOR-Mediated Autophagy Is Involved in the Protective Effect of Ketamine on Allergic Airway Inflammation Hongyun Zou, et al,Journal of Immunology Research,2019
Estrogen ameliorates allergic airway inflammation via regulating the activation of NLRP3 inflammasome in mice Cheng C, et al,Bioscience Reports,2018
Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation Lixia Wang .et al,Journal of Immunology Research,2018
Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation. Shen QY.et al,Respirology.,2015
JNK-TLR9 signal pathway mediates allergic airway inflammation through suppressing melatonin biosynthesis Wu HM.et al,J Pineal Res.,2016
Comparison of exercise treadmill test, flow mediated dilatation, and inflammation in individuals with low risk of adverse cardiovascular events Muhammed Sait Toprak. et al,Asian Biomedicine,2015
SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model Wu HM. et al,Mol Immunol. ,2015

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Mouse ovalbumin specific IgE,OVA sIgE ELISA Kit

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Test parameter	specification	test result
Positive control	>0.8	1.506
Negative control	<0.2	0.176
Positive rate	10，Positive	100%
Negative rate	10，Negative	100%