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中文名称:小鼠胰岛素自身抗体(IAA)酶联免疫试剂盒
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货号:CSB-E10369m
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规格:96T/48T
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价格:¥3200/¥2500
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其他:
产品详情
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产品描述:CUSABIO小鼠胰岛素自身抗体(IAA)酶联免疫检测试剂盒(货号:CSB-E10369m),采用间接ELISA原理定性检测血清或血浆样本中的IAA水平。IAA是自身免疫性糖尿病的重要标志物,在1型糖尿病模型研究中可作为评估胰岛β细胞自身免疫损伤的早期指标,为探索疾病发生机制提供关键数据支持。本试剂盒通过包被胰岛素抗原捕获样本中的IAA,经酶标二抗催化显色反应,最终通过OD值判定抗体存在与否。其高特异性设计适用于科研场景中糖尿病动物模型的自身免疫状态评估,如监测疾病进展、评价药物干预对自身抗体水平的影响,或用于胰岛自身免疫相关分子机制研究。实验需根据标准操作流程进行,具体检测范围可咨询技术支持获取。该产品仅限科学研究使用,实验结果需结合其他指标综合分析。
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缩写:IAA
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种属:Mus musculus (Mouse)
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样本类型:serum, plasma
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检测范围:Request Information
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灵敏度:Request Information
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Others
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测定原理:qualitative
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测定方法:Indirect
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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标准曲线:
Test parameter
specification
test result
Positive control
>0.8
1.787
Negative control
<0.2
0.093
Positive rate
10,Positive
100%
Negative rate
10,Negative
100%
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货期:3-5 working days
引用文献
- TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes DA Abdulabbas,Nature communications,2024
- Tyk2-mediated signaling promotes the development of autoreactive CD8+ CTLs and autoimmune type 1 diabetes K Mine,bioRxiv,2023
- Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling Q Yuan,Journal of Diabetes Research,2022
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