Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

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中文名称：

小鼠Ⅰ型胶原C端肽(CTX-Ⅰ)酶联免疫试剂盒
货号：

CSB-E12782m
规格：

96T/48T
价格：

￥3600/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

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产品描述：

CUSABIO小鼠Ⅰ型胶原C端肽（CTX-Ⅰ）酶联免疫检测试剂盒（货号：CSB-E12782m），采用竞争法原理实现定量分析，适用于血清、血浆及组织匀浆样本的检测。CTX-Ⅰ是Ⅰ型胶原蛋白分解代谢的关键产物，其浓度变化可反映骨基质降解活性，常用于骨代谢异常、骨质疏松模型研究及骨相关疾病的机制探索。本试剂盒检测范围为0.23-15 ng/ml，最低可稳定检测至0.23 ng/ml，实验仅需50 μL样本量即可完成检测，通过预包被的抗体与样本中CTX-Ⅰ及标记物的竞争性结合实现定量分析，操作流程标准化，重复性良好。科研场景中可用于评估骨吸收标志物水平，例如在骨质疏松动物模型中动态监测骨质流失程度，或结合药物干预实验探究骨代谢调控机制。试剂盒组分经过严格质控，包含标准品、检测抗体及显色底物，支持科研人员高效完成骨代谢相关的基础研究与药效评价。
别名：

cross linked C-telopeptide of type 1 collagen (CTX-1),_x000D_cross linked C-telopeptide of type I collagen (CTX-I)
缩写：

CTX-Ⅰ
种属：

Mus musculus (Mouse)
样本类型：

serum, plasma, tissue homogenates.
检测范围：

0.23 ng/ml-15 ng/ml.
灵敏度：

0.12 ng/ml.
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Others
测定原理：

quantitative
测定方法：

Competitive

精密度：

线性度：

To assess the linearity of the assay, samples were spiked with high concentrations of mouse CTX-Ⅰ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:1	Average %	84
	Range %	80-92
1:2	Average %	87
	Range %	81-94
1:4	Average %	88
	Range %	82-95
1:8	Average %	93
	Range %	86-98

回收率：

标准曲线：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml

OD1

OD2

Average

0.195

0.204

0.200

7.5

0.246

0.260

0.253

3.75

0.339

0.348

0.344

1.87

0.518

0.529

0.524

0.94

0.851

0.841

0.846

0.47

1.272

1.253

1.262

0.23

1.838

1.784

1.811

2.512

2.525

2.518

数据处理：

ELISA操作视频及标曲绘制软件下载
货期：

3-5 working days

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最新研究进展：

Ⅰ型胶原交联脱氨酸肽（CTX-Ⅰ）是胶原蛋白分解产物之一，它被认为是骨吸收的生物标志物之一。CTX-Ⅰ的检测可以用于评估骨吸收水平，是一种广泛应用的临床诊断指标。最近的研究表明，CTX-Ⅰ还与一些非骨代谢方面的疾病有关，例如心血管疾病、糖尿病、肾脏疾病等。

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.