Mouse Soluble Cluster of differentiation 30 ligand,sCD30L ELISA Kit
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中文名称：小鼠可溶性CD30配体(sCD30L)酶联免疫试剂盒
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货号：CSB-E04715m
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规格：96T/48T
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价格：￥3200/￥2500
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其他：
产品详情
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产品描述：小鼠可溶性CD30配体(sCD30L)酶联免疫试剂盒（CSB-E04715m）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的TNFSF8含量。TNFSF8是重要靶点。它属肿瘤坏死因子超家族，参与免疫调节。探索它与免疫细胞相互作用及信号传导过程，期望通过调控它治疗肿瘤、自身免疫病等，为开发新疗法提供理论依据和方向。试剂盒检测范围为15.6 pg/mL-1000 pg/mL，适用于评估感染、自身免疫疾病等实验模型中sCD30L的表达调控，为研究T细胞活化、淋巴组织发育及免疫相关疾病机制提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：Tnfsf8; Cd30l; Cd30lg; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD antigen CD153
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缩写：
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Uniprot No.：
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种属：Mus musculus (Mouse)
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样本类型：serum, plasma, tissue homogenates
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检测范围：0.156 ng/ml - 10 ng/ml
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灵敏度：0.039 ng/ml
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Others
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货期：3-5 working days
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靶点详情
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功能：Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
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基因功能参考文献：
- Altered expression of CD30L and IL-3 may be potential biomarkers for hepatotoxicity induced by D. bulbifera. PMID: 24647110
- It is shown here that CD30L knock out (KO) mice are highly susceptible to primary infection with Listeria monocytogenes as assessed by the survival rate. PMID: 21699557
- Modulation of CD30L/CD30 signaling by soluble CD30 could be a novel biological therapy for inflammatory diseases associated with Th17 responses. PMID: 21068411
- Characterization of the murine CD30 ligand (CD153) gene: gene structure and expression. PMID: 12392508
- CD30L is required for generation of long-lived memory CD8+ T cells; CD30L signaling triggers homing receptors for T(central memory) cells. PMID: 16177108
- Signaling executed by CD30positive T cell interaction with CD30Lpositive T cells plays a critical role in amplification of T helper type (Th)1 responses able to produce interferon-gamma against Mycobacterium bovis bacillus Calmette-Guerin infection. PMID: 18941223
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亚细胞定位：Membrane; Single-pass type II membrane protein.
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蛋白家族：Tumor necrosis factor family
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数据库链接：
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