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Mouse Secretoglobin family 3A member 1(SCGB3A1) ELISA kit

  • 中文名称:
    小鼠分泌球蛋白家族3A成员1(SCGB3A1)酶联免疫试剂盒
  • 货号:
    CSB-EL020818MO
  • 规格:
    96T/48T
  • 价格:
    ¥3600/¥2500
  • 其他:

产品详情

  • 产品描述:
    小鼠分泌球蛋白家族3A成员1(SCGB3A1)酶联免疫试剂盒(CSB-EL020818MO)为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的SCGB3A1含量。SCGB3A1是呼吸道上皮分泌蛋白,在肺组织等有表达。其与肺部疾病如肺纤维化、肺癌等密切相关。研究机制上,它参与调节肺部炎症反应、细胞增殖与分化,有望作为生物标志物用于疾病诊断及治疗靶点开发。试剂盒检测范围为62.5 pg/ml-4000 pg/ml,适用于科研领域中小鼠肺部疾病模型、气道炎症机制研究、基因修饰动物模型的表型验证等场景,为探索SCGB3A1在呼吸系统病理生理过程中的功能提供可靠工具。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
  • 别名:
    Scgb3a1 ELISA Kit; Hin1 ELISA Kit; Pnsp2 ELISA Kit; Ugrp2 ELISA Kit; Secretoglobin family 3A member 1 ELISA Kit; Cytokine HIN-1 ELISA Kit; High in normal 1 ELISA Kit; Pneumo secretory protein 2 ELISA Kit; PnSP-2 ELISA Kit; Uteroglobin-related protein 2 ELISA Kit
  • 缩写:
    SCGB3A1
  • Uniprot No.:
  • 种属:
    Mus musculus (Mouse)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    62.5 pg/ml -4000 pg/ml
  • 灵敏度:
    15.6 pg/ml
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Cancer
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 功能:
    Secreted cytokine-like protein. Inhibits cell growth in vitro.
  • 基因功能参考文献:
    1. Neonatal hyperoxia followed by RA recovery was associated with decreased lung CCSP and SCGB3A1 protein but not mRNA expression. PMID: 24187664
    2. The differential expression of mRNA by both airway level and lung region was determined for uteroglobin-related protein 2. PMID: 20852037
    3. Highest HIN-1 and UGRP-1 expression is detected in the lung, while lower level HIN-1 expression is also detected in the stomach, heart, small intestine, uterine and mammary glands PMID: 12175512
    4. genomic structure and expression patterns of Ugrp2 and its alternative spliced form were characterized PMID: 12438750
    5. EGF-induced increase of Ugrp2 occurred at the transcriptional level that required the EGF receptor and the activation of the ERK-MAPK and phosphoinositide-3 kinase pathways PMID: 15811345
    6. ubiquitous transcription factor NF-Y binds to and activates expression of the Scgb3a1 gene and tissue-specific expression of the gene is associated with CpG methylation of the promoter PMID: 18194566
    7. The expression of SCGB3A1 and SCGB3A2 are bidirectionally regulated by oncostatin M (OSM) when examined in a mouse transformed Clara cell line. PMID: 18978304
    8. Expression of SCGB3A1 was down-regulated by IFN-gamma in a time- and dose-dependent manner in the murine transformed Clara Cells line. PMID: 19135978

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  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    Secretoglobin family, UGRP subfamily
  • 组织特异性:
    Highly expressed in lung, where it localizes to epithelial cells lining the trachea and bronchi. Expression in lung is mainly restricted to bronchi, submucosal glands of the trachea, and tracheal epithelium, with little expression in terminal bronchioles.
  • 数据库链接: